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Valsartan Valsartan trade name Diovan is an angiotensin II receptor antagonist commonly called an ARB, or angiotensin receptor blocker, that is selective for the type I AT1 angiotensin receptor Valsartan is mainly used for treatment of high blood pressure, congestive heart failure, and to increase the chances of living longer after a heart attack Contents 1 Medical uses 2 Contraindications 3 Side effects 31 Heart failure 32 Hypertension 4 Interactions 5 Mechanism of action 6 Economics 7 Research 8 Combination drugs 9 See also 10 References 11 External links Medical uses Valsartan is used to treat high blood pressure, congestive heart failure, and to reduce death for people with left ventricular dysfunction after having had a heart attack12 There is contradictory evidence with regard to treating people with heart failure with a combination of an angiotensin receptor blocker like valsartan and an angiotensin-converting enzyme inhibitor, with two major clinical trials CHARM-additive and ValHeFt showing a reduction in death, and two others VALIANT and ONTARGET showing no benefits, a Valsartan Click for more; https://www.turkaramamotoru.com/en/valsartan-24415.html There are excerpts from wikipedia on this article and video
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Chinese company recalls tainted heart medicine from stores worldwide
(CNN)A medicine manufacturer in China is undertaking an international recall of active substances used in a commonly-used heart medicine which were found to contain traces of a dangerous carcinogen, the government announced Sunday.It is the second major Chinese medical controversy in less than a month, after hundreds of thousands of children's vaccines were revealed to be faulty, putting an unknown number of infants at risk.Valsartan, a drug used to treat high-blood pressure and prevent heart failure, was recalled in 22 countries across Europe and North America earlier in July after batches were found to contain N-nitrosodimethylamine (NDMA), an organic chemical that belongs to a family of potent carcinogens. The substances were supplied by Zhejiang Huahai Pharmaceuticals (ZHP), based in Linhai, in eastern China, who said they notified authorities as soon as they identified the impurity."We published our recall notice at midday on July 13 in China and overseas, and published the US market recall notice on July 14 Beijing time ... all the drug materials for the Chinese market were recalled by July 23," the company said in a statement to the Shanghai stock exchange Monday. Read MoreOn July 16, ZHP said it had pulled all Valsartan products from US pharmacies, a market worth $20 million in sales for the company in 2017. Animal studies using NDMA have shown it to cause liver, kidney and respiratory track tumors. Following the revelation, China's Food and Drug Administration said it had conducted a screening of all the country's suppliers of the Valsartan ingredients, including ZHP. The early recall involved around 2,300 batches of the ingredient. Among the countries it was sent to were Germany, Canada, France, and Sweden. According to Xinhua, ZHP has taken "needed measures" to put it back in line with regulations.China's reputation at riskThe recent drug scandals come at a time when the Chinese government is attempting to rebuild trust, both domestically and internationally, in the quality of the country's products.The government announced in mid-July it had discovered an estimated 250,000 doses of a diphtheria and tetanus (DPT) vaccine made by Changchun Changsheng Biotechnology and intended for young children were faulty, sparking widespread panic.Vaccine scandal exposes the contradictions at the heart of the 'Chinese dream'So far, 15 people have been detained, including the company's chairman, Gao Junfang, but the reaction on China's social media was fast and fierce before censors intervened."My home country, how can I trust you? You just let me down again and again," one user commented on social media.Just days before the DPT vaccine announcement, more than 100,000 doses of a rabies vaccine produced by the same company were also found to be defective.Major international scandals have badly damaged the country's reputation, such as the 2008 tainted milk formula scandal which put thousands of children at risk.More recently in 2016, a criminal organi
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