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Видео добавленное пользователем “Demystifying Medicine”
Polycystic Ovarian Syndrome (PCOS) Pathophysiology
 
02:17
This video looks at the pathophysiology of polycystic ovarian syndrome (PCOS).
Просмотров: 20042 Demystifying Medicine
An Overview of Scleroderma Part 1: Breaking it down
 
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Please see part 2 here: https://www.youtube.com/watch?v=6KLeGkeREkM Scleroderma is derived from the Greek words, sclero meaning hardness and derma meaning skin, literally meaning hard skin. It is an autoimmune disease that involves overproduction of collagen which results in the hardening, tightening and scarring of skin and internal organs. It affects about 2.5 million people worldwide. This video is Part 1 of 2, in which we will discuss the different forms of scleroderma and the problems associated with each of them, in hope that you will be more informed about this complicated disease. This video was created by McMaster Demystifying Medicine students Nabeelah Khan, Andrew Nguyen, Helen Kim, Tosin Tomiwa, Kosalan Akilan, and Justin Lu for McMaster’s Demystifying Medicine seminar series. Copyright McMaster University 2015. Links for more information on scleroderma: Scleroderma Society of Ontario http://www.sclerodermaontario.ca/index.html Hamilton Scleroderma Group http://www.hamiltonscleroderma.org/ References: Pope, J. E., & Johnson, S. R. (2015). New Classification Criteria for Systemic Sclerosis (Scleroderma). Rheumatic Disease Clinics of North America. Scleroderma Diagnosis - Scleroderma Health Information - NY Times Health [Internet]. 2015. Available from: http://www.nytimes.com/health/guides/disease/scleroderma/diagnosis.html
Просмотров: 54022 Demystifying Medicine
Life After Sepsis: Health Consequences Among Survivors of Severe Sepsis
 
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Each year millions of patients worldwide suffer from an episode of severe sepsis. With advances in early detection and antibiotic therapy, the majority of these patients are released from the hospital and appear to be healthy. However, it has been suspected that many are discharged with a new, poorly understood array of long-term cognitive and functional impairments. This video defines sepsis, outlines the current evidence for long-term impairment and discusses the implications of these findings. Video by Aaron Edward, Hussain Abbas, Sarah Gabrial, Renuka Singh and Justin Wu Copyright McMaster University 2016 References 1. Angus, D., & Poll, T. Van Der. (2013). Severe sepsis and septic shock. New England Journal of Medicine, 369, 840–51. 2. Cuthbertson, B. H., Elders, A., Hall, S., Taylor, J., Maclennan, G., Mackirdy, F., & Audit, G. (2013). Mortality and quality of life in the five years after severe sepsis. Critical Care, 17(2), R70. 3. Langa, K. M., & Iwashyna, T. (2012). Long-term cognitive impairment and functional disability among survivors of severe sepsis. JAMA, 304(16), 1787–1794. 4. Yende, S., & Angus, D. C. (2007). Long-term outcomes from sepsis. Current Infectious Disease Reports, 9, 382-386.
Просмотров: 23116 Demystifying Medicine
Depression: A Student's Perspective
 
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This video educates students about depression in order to minimize the stigma that is associated with the medical condition. It discusses how depression impacts lives and describes its symptoms, causes and treatment options. The video also provides information about resources available at McMaster University for students who are living with depression. This video was made by 4DM3 students Zunaira Tarique, Shatha Jaber, Semir Bulle and Haley Leroux Copyright McMaster University 2017 Please let us know how you liked this video and suggest additional topics for us to attempt to demystify below. References: Aan het Rot, M., Mathew, S. J., & Charney, D. S. (2009). Neurobiological mechanisms in major depressive disorder. CMAJ : Canadian Medical Association Journal, 180(3), 305–313. http://doi.org/10.1503/cmaj.080697 Canadian Mental Health Association. (2016). Stigma and Discrimination. Retrieved http://ontario.cmha.ca/mental-health/mental-health-conditions/stigma-and-discrimination/ Kanter, J. W., Busch, A. M., Weeks, C. E., & Landes, S. J. (2008). The Nature of Clinical Depression: Symptoms, Syndromes, and Behavior Analysis. The Behavior Analyst, 31(1), 1–21. MacGil, M. (2016). Depression: causes, symptoms, and treatments. Retrieved: http://www.medicalnewstoday.com/kc/depression-causes-symptoms-treatments-8933#depression_symptoms Psych Guides. (2016). Depression Symptoms, Causes, and Effects. Retrieved: http://www.psychguides.com/guides/depression-symptoms-causes-and-effects/ Stengler-Wenzke, K., Angermeyer, M. C., & Matschinger, H. (2000). Depression and stigma. Psychiatrische Praxis, 27(7), 330-335.
Просмотров: 367575 Demystifying Medicine
Balancing the Bones: Blood Calcium Homeostasis
 
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This short animated video presentation describing the basics of bone remodeling and calcium metabolism as well as the multiple functions of Vitamin D. Furthermore, this animation introduces the concept of homeostasis and hormone feedback loops in which the parathyroid and thyroid work to maintain specific blood-calcium levels. This animation was prepared by 4DM3 students Daniel Weiss, Janet Zanin, Rebecca Stepita & Olivia Cook
Просмотров: 28111 Demystifying Medicine
How Do MRI, PET and CAT Scans Work?
 
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Major advancements in the field of medical imagining now allow healthcare providers to see a clear visual representation of the situation inside a person’s body. This video discusses three of the most commonly used medical imaging techniques: MRI, PET and CAT scans. In three hypothetical scenarios, the video compares and contrasts the three methods in terms of their advantages to the specific medical situation and risks to the patients. An MRI creates a clear image of the body without posing a serious risk to the patient due to its lack of ionizing radiation. The clarity and detail of a CAT scan is a focal point when comparing these three techniques, despite its increased risk of cancer due to the ionizing radiation it exposes the patient to. Due to its 3-dimension cross sectional pictures, CAT scans can be used in a great range of medical complications including detection of cancer. By using radioactive tracers, a PET scan differs from the first two techniques in its ability to provide information about organ function rather than just structure. It provides valuable information about functions such as glucose metabolism, oxygen use and blood flow. The PET scan can also provide information at a cellular level. Finally, the video presents the steps that patients should take to prepare for these tests such as mentioning any previous medical conditions, pregnancy and the presence of metal anywhere on or inside the body which could hinder the results, especially in the MRI and CAT scan. Video by Zubair Banoor, Jaskeerat Kaur, Sina Nastarani, Kritika Seth and Monica Persaud Copyright McMaster University 2016 Please let us know how you liked this video and suggest additional topics for us to demystify below.
Просмотров: 73655 Demystifying Medicine
Do Learning Styles Really Exist?
 
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The idea of learning styles is widespread throughout the field of pedagogy and people are often categorized according to their learning style. However, in scientific research, there has been no credible evidence that supports the existence of learning styles. This video defines learning styles theory, talks about some previous research in the field of pedagogy and explains why there is no true basis behind the idea of learning styles. In addition, Dr. Joseph Kim, an associate professor of psychology, neuroscience and behaviour at McMaster University, speaks about the non-existence of learning styles. This video was created by fourth year McMaster students interested in education and knowledge translation: Dana Abu-Jazar, Ana Kovacevic, Amber Kayed, Jasleen Khaira, Babak Nouhi, Simranpal Dhanju, Ria Oommen, and Nisha Gajaria. Copyright McMaster University 2014 References: Kratzig, Gregory, and Katherine Arbuthnott. "Perceptual Learning Style and Learning Proficiency: A Test of the Hypothesis." Journal of Educational Psychology (2006). Salomon, Gavriel. "Television Is "easy" and Print Is "tough": The Differential Investment of Mental Effort in Learning as a Function of Perceptions and Attributions." Journal of Educational Psychology 76.4 (1984).
Просмотров: 56823 Demystifying Medicine
The ABCD’s of Vitamins
 
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Vitamins are essential substances that our body needs in order to grow, develop normally and maintain its functions. This videos covers vitamins A, B, C and D and their functions in the human body, ways where we can obtain them in our diet and the health outcomes when there is a deficiency in our body. This video was created by a group of McMaster University students in a knowledge translation course for the Demystifying Medicine series: Soheil El-azzouni, Stanley Chen, Sara Halawa, Yuxin (Tiffany) Tian and Kimberly Young. Copyright McMaster University 2014
Просмотров: 242392 Demystifying Medicine
What Is Cystic Fibrosis?
 
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This video presents information about cystic fibrosis (CF), which is an autosomal recessive disorder. The video outlines the basic biological principles behind CF, along with an overview of the disease and available treatment options. The video begins by mentioning the genetic mutation to the cystic fibrosis transmembrane conductance regulatory (CFTR) gene on chromosome 7 which is the main cause of CF. Subsequently, the video entails the symptoms of the disease, including increased perspiration, pancreatic insufficiencies and lung infections. The epidemiology of this disease is also mentioned as the video states that 1 in 3600 children born in Canada is affected by CF. Furthermore, a significant portion of the video explains the organs affected by the disease and any treatment options that patients have. It is thoroughly explained that CF affects multiple organs including the lungs, pancreas and intestines. Many of these complications are due to blockages caused by the buildup of mucus. For instance, blockages caused in the intestines due to mucus buildup creates inefficiencies in digestion, specifically for fats and proteins. Considering there are multiple body parts affected by CF, there is a wide range of treatment options available to alleviate the condition of the disease. A majority of the treatment options serve the function of removing buildups of mucus and the blockages that occur. A patient with CF will most likely experience lung infections which are often treated with different types of antibiotics based on the severity of the disease and type of bacteria that is present. Other medications, most notably, bronchodilators, are also considered as treatment options for this disease. Lastly, there are also physical treatments such as Chest Physical Therapy (CPT) which also attempt to clear mucus using physical techniques. Overall, our video attempts to explain the basic processes that cause CF, subsequently followed by its overall impact on the patient’s body and the treatments that are available. This video was made by 4DM3 students Zubair Banoor, Jaskeerat Kaur, Sina Nastarani, Monica Persaud and Kritika Seth Copyright McMaster University 2016 Please let us know how we can improve our videos and additional topics should be addressed below.
Просмотров: 57118 Demystifying Medicine
Walk In My Shoes: ADHD
 
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Many people can relate to the times when they were unable to fully concentrate, couldn’t regain focus, drifted from task to task, or were unable to sit still in their seat. Most people can relate to these behaviours, but when they’re a constant part of a person’s life, a patient may be diagnosed with Attention Deficit Hyperactivity Disorder (ADHD). This video looks at the life of a person with a common form of ADHD, and delves into a list symptoms to help raise awareness about this disorder and its effects on individuals due to atypical brain functions. However, it’s no cause for alarm! We’ll end off our discussion with common research-supported strategies to cope with this disorder so as to live a regular functional life. This is the first instalment of our interactive video series "Walk In My Shoes," where we’ll be raising awareness and learning from the lives of individuals afflicted with learning disorders. This video was created by Demystifying Medicine students Shara Chowdhury, Vanessa Miranda, Mishaal Qazi, and Peter Tso. Copyright McMaster University 2017 References: Charach, A., Skyba, A., Cook, L., & Antle, B. J. (2006). Using Stimulant Medication for Children with ADHD: What Do Parents Say? A Brief Report.Journal of the Canadian Academy of Child and Adolescent Psychiatry, 15(2), 75–83. Coletti, D. J., Pappadopulos, E., Katsiotas, N. J., Berest, A., Jensen, P. S., & Kafantaris, V. (2012). Parent Perspectives on the Decision to Initiate Medication Treatment of Attention-Deficit/Hyperactivity Disorder. Journal of Child and Adolescent Psychopharmacology, 22(3), 226–237. http://doi.org/10.1089/cap.2011.0090 Kolar, D., Keller, A., Golfinopoulos, M., Cumyn, L., Syer, C., & Hechtman, L. (2008). Treatment of adults with attention-deficit/hyperactivity disorder. Neuropsychiatric Disease and Treatment, 4(2), 389–403. Lou, H. C., Henriksen, L., & Bruhn, P. (1984). Focal cerebral hypoperfusion in children with dysphasia and/or attention deficit disorder. Archives of neurology, 41(8), 825-829. Millstein, R. B., Wilens, T. E., Biederman, J., & Spencer, T. J. (1997). Presenting ADHD symptoms and subtypes in clinically referred adults with ADHD. Journal of Attention Disorders, 2(3), 159-166. Rubia, K. (2002). The dynamic approach to neurodevelopmental psychiatric disorders: use of fMRI combined with neuropsychology to elucidate the dynamics of psychiatric disorders, exemplified in ADHD and schizophrenia. Behavioural brain research, 130(1), 47-56. Rubia, K., Overmeyer, S., Taylor, E., Brammer, M., Williams, S. C., Simmons, A., & Bullmore, E. T. (1999). Hypofrontality in attention deficit hyperactivity disorder during higher-order motor control: a study with functional MRI. American Journal of Psychiatry, 156(6), 891-896. Sonuga-Barke, E. J., Dalen, L., Daley, D., & Remington, B. (2002). Are planning, working memory, and inhibition associated with individual differences in preschool ADHD symptoms?. Developmental neuropsychology, 21(3), 255-272. Sullivan, K., Hatton, D., Hammer, J., Sideris, J., Hooper, S., Ornstein, P., & Bailey, D. (2006). ADHD symptoms in children with FXS. American Journal of Medical Genetics Part A, 140(21), 2275-2288.
Просмотров: 42121 Demystifying Medicine
Basics of Organ Rejection
 
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This video provides information about how the human immune system protects you against foreign bodies through the recognition of antigens. From there, it examines how this very same process can also work against a patient during organ transplantation and can ultimately lead to organ rejection. Furthermore, it discusses the different forms of organ rejection. Finally, it looks at the future of organ transplantation by discussing potential alternatives which include stem cells generated organs, and bioartificial organs that could potentially eliminate the risk of organ rejection completely. This video was made by 4DM3 students Mateen Akhtar, Tamandeep Khangura, Andrew Nashed, Humaira Nakhuda and Vyshnavi Mahendran Please let us how you like this video and if you have any suggestions to how we can improve our videos. Copyright McMaster University 2016 References: London Health Sciences Centre (n.d.). Multi-Organ Transplant Program. Retrieved from: http://www.lhsc.on.ca/About_Us/MOTP/Statistics/ Martin, L., Zieve, D., & Ogilive, I. (2015). Transplant Rejection. MedlinePlus: Trusted Health Information for You. Retrieved from: https://medlineplus.gov/ency/article/000815.htm   Sifferlin, A. (2013). 5 Discoveries That Will Change The Future of Organ Transplants. Time. Retrieved from: http://healthland.time.com/2013/06/06/5-discoveries-that-will-change-the-future-of-organ-transplants/slide/transplants-without-the-drugs/ Tushla, L. (n.d.) When A Transplant Fails. National Kidney Foundation. Retrieved from: https://www.kidney.org/transplantation/transaction/TC/summer09/TCsm09_TransplantFails    World Health Organization (n.d.). Transplantation: Donation and Transplantation. Retrieved from: http://www.who.int/transplantation/donation/en/
Просмотров: 18308 Demystifying Medicine
What Is Chronic Fatigue Syndrome?
 
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This video delves into the underlying mechanisms, symptoms, lifestyle and treatment associated with chronic fatigue syndrome. The purpose of this video is to educate a general audience about chronic fatigue syndrome, its diagnosis, and treatment (or lack of treatment options). Please look at the following links to gain more information: PACE trial reanalysis: https://t.co/aPGuX9aIpg and https://t.co/as6cZKsf6h PACE trail: https://www.ncbi.nlm.nih.gov/pubmed/21334061 This video was made by Demystifying Medicine students: Sabrina Garritano, Angelica Dimita, Hayley Duff, and Desmond Chan Copyright McMaster University 2018 References Courage, K. H. (2014). Baffling chronic fatigue syndrome set for diagnostic overhaul. Scientific American. Retrieved from https://www.scientificamerican.com/article/baffling-chronic-fatigue-syndrome-set-for-diagnostic-overhaul/ Lorusso, L., Mikhalova, S. V., Capelli, E., Ferrari, D., Ngonga, G. K., & Ricevuti, G. (2008). Immunological aspects of chronic fatigue syndrome. Autoimmunity Reviews. doi:i:10.1016/j.autrev.2008.08.003 Mayo Clinic. (2018). Chronic fatigue syndrome. Retrieved from https://www.mayoclinic.org/diseases- conditions/chronic-fatigue-syndrome/symptoms-causes/syc-20360490 Mayo Clinic. (2018, January 05). Chronic fatigue syndrome - Diagnosis and Treatment. Retrieved March 19, 2018, from https://www.mayoclinic.org/diseases-conditions/chronic-fatigue-syndrome/diagnosis-treatment/drc-20360510 O’Rourke, M. (2015). A new name, and wider recognition, for chronic fatigue syndrome. The New Yorker. Retrieved from https://www.newyorker.com/tech/elements/chronic-fatigue-syndrome- iom-report White, P. D., Goldsmith, K. A., Johnson, A. L., Potts, L., Walwyn, R., DeCesare, J. C., ... & Bavinton, J. (2011). Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (PACE): a randomised trial. The Lancet, 377(9768), 823-836. Rehmeyer, J., & Tuller, D. (2017). Getting it wrong on chronic fatigue syndrome. The New York Times. Retrieved from https://www.nytimes.com/2017/03/18/opinion/sunday/getting-it-wrong-on-chronic-fatigue-syndrome.html Rowe, P. C., Underhill, R. A., Friedman, K. J., Gurwitt, A., Medow, M. S., Schwartz, M. S., ... & Rowe, K. S. (2017). Myalgic encephalomyelitis/chronic fatigue syndrome diagnosis and management in young people: a primer. Frontiers in pediatrics, 5, 121. Wilshire, C., Kindlon, T., Matthees, A., & McGrath, S. (2017). Can patients with chronic fatigue syndrome really recover after graded exercise or cognitive behavioural therapy? A critical commentary and preliminary re-analysis of the PACE trial. Fatigue: Biomedicine, Health & Behavior, 5(1), 43-56. Yancey, J. R., & Thomas, S. M. (2012). Chronic fatigue syndrome: diagnosis and treatment. Am Fam Physician, 86(8), 741-746.
Просмотров: 18485 Demystifying Medicine
Busting Sexual Health Myths - What is a Hymen?
 
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There are many misconceptions regarding the hymen. Learn more about this mysterious organ so you can make safe and educated decisions about your body. This video was made by Health Science 4DM3 students Saima Ahmad, Atherai Maran, Candy Niu, and Joy Sumin Park. Copyright McMaster University 2017 References: Adams, J. A., Botash, A. S., & Kellogg, N. (2004). Differences in hymenal morphology between adolescent girls with and without a history of consensual sexual intercourse. Archives of pediatrics & adolescent medicine, 158(3), 280-285. American Academy of Pediatrics. (2004). Virginal Myths Regarding the Intact Hymen. AAP Grand Rounds, 11(6), 67-67. Castleman, M., M.A. (n.d.). The Hymen: A Membrane Widely Misunderstood. Retrieved from https://www.psychologytoday.com/blog/all-about-sex/201103/the-hymen-membrane-widely-misunderstood Cinthio, H. (2015). “You go home and tell that to my dad!” Conflicting Claims and Understandings on Hymen and Virginity. Sexuality & Culture, 19(1), 172-189. Hegazy, ABDELMONEM AWAD, and M. O. Al-Rukban. "Hymen: facts and conceptions." The Health 3.4 (2012): 109-115. Hymen Greek Mythology. (n.d.). Retrieved from https://www.britannica.com/topic/Hymen-Greek-mythology Loeber, O. (2015). Wrestling with the hymen: Consultations and practical solutions. The European Journal of Contraception & Reproductive Health Care, 20(2), 128-135. O'connell, H. E., Eizenberg, N., Rahman, M., & Cleeve, J. (2008). The anatomy of the distal vagina: Towards unity. The journal of sexual medicine, 5(8), 1883-1891. Raveenthiran, V. (2009). Surgery of the hymen: from myth to modernisation. Indian Journal of Surgery, 71(4), 224-226. Van Moorst, B. R., van Lunsen, R. H., van Dijken, D. K., & Salvatore, C. M. (2012). Backgrounds of women applying for hymen reconstruction, the effects of counselling on myths and misunderstandings about virginity, and the results of hymen reconstruction. The European Journal of Contraception & Reproductive Health Care, 17(2), 93-105.
Просмотров: 15902 Demystifying Medicine
Idiopathic Pulmonary Fibrosis: The Simple Facts
 
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This simple video presents a basic understanding of idiopathic pulmonary fibrosis (IPF). This fatal condition does not have a known cause, and research investigating its pathology is ongoing. This video was created by Health Science 4DM3 students Adrienne Lee, Kim Rod, Patrick Rudak, Ria Oommen and Shylendra Mahendran, in an effort to increase awareness and understanding about IPF. © 2015. McMaster University. All Rights Reserved.
Просмотров: 25984 Demystifying Medicine
Type 2 Diabetes: Understanding the Link Between Obesity & Type 2 Diabetes
 
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Videos prepared by Steven Liang (BHSc), Tegan O'Brien (Arts and Science), Darren Liu (BHSc), Vitheya Thanabalan (Life Sciences) Type 2 diabetes has become a pandemic and is showing no signs of slowing down. Today, the estimated worldwide prevalence of type 1 and 2 diabetes is close to 300 million. This number is predicted to rise to 439 million by 2030, with type 2 diabetes accounting for about 90% of these cases. Individuals with type 2 diabetes are often told by their doctors that their disease can be effectively managed with healthy eating, regular exercise and blood sugar monitoring. These students have created a series of three videos that simplify the complex disease process of type 2 diabetes in the hopes that better understanding will motivate patients to better manage their disease. In this video, the students uses animation to show how obesity can increase a person's risk of getting diabetes by inducing insulin resistance. Learning objectives: - Understand the disease mechanisms underlying type 2 diabetes - Understand the link between obesity and insulin resistance - Understand the negative impacts of high blood glucose - Learn why it is so important to effectively manage Type 2 diabetes
Просмотров: 14032 Demystifying Medicine
Clinical Trials: It’s not just a phase!
 
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This video covers the role of clinical trials within the drug development process in Canada. These trials have multiple phases, with each having a specific purpose in order to test the safety, dosage and efficacy of the drug. Additionally, the risks and benefits to participants are covered for individuals who are considering participating in a trial. This video was made by 4DM3 students Erika Opingari, Brenton Wong, Coomal Rashid, Healey Schulman and Kavena Sivakumar Please let us how you like this video and if you have any suggestions to how we can improve our videos. Copyright McMaster University 2016 1. Government of Canada HC. Guidance Document For Clinical Trial Sponsors: Clinical Trial Applications [Internet]. 2003 [cited 2016 Nov 2]. Available from: http://www.hc-sc.gc.ca/dhp-mps/prodpharma/applic-demande/guide-ld/clini/ctdcta_ctddec-eng.php 2. Government of Canada HC. It’s Your Health - Clinical Trials and Drug Safety [Internet]. 2013 [cited 2016 Nov 2]. Available from: http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/clinical_trials-essais_cliniques-eng.php 3. Government of Canada HC. How Drugs are Reviewed in Canada [Internet]. 2001 [cited 2016 Nov 2]. Available from: http://www.hc-sc.gc.ca/dhp-mps/prodpharma/activit/fs-fi/reviewfs_examenfd-eng.php 4. Benefits and risks of clinical trials - Canadian Cancer Society [Internet]. www.cancer.ca. [cited 2016 Nov 2]. Available from: http://www.cancer.ca/en/cancer-information/diagnosis-and-treatment/clinical-trials/benefits-and-risks-of-clinical-trials/?region=on 5. FAQClinicalTrials.gov - Benefits and Risks of Clinical Trials [Internet]. [cited 2016 Nov 2]. Available from: https://www.nlm.nih.gov/services/ctbenefits.html
Просмотров: 7374 Demystifying Medicine
An Overview of Scleroderma Part 2: Treatment and management
 
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Watch Part 1 here: https://www.youtube.com/watch?v=h6ti1eVo-9s Scleroderma, an autoimmune disease that has no current cure, can be debilitating and drastically change the lives of those that are affected. In severe cases, scleroderma can affect the whole body by spreading to multiple organ systems. Although its associated symptoms can be severe, they can be largely reduced if scleroderma is detected in its early stages and properly managed. This video is the second part of two videos that outlines the treatment and management of this disease and various resources available that can help those that are affected by scleroderma. This video was created by McMaster Demystifying Medicine 4DM3 students: Andrew Nguyen, Nabeelah Khan, Thilini Delungahawatta, Mark Hwang, Sinthu Pathmanapan and Wayne Yeung. Copyright McMaster University 2015. Here are some resources to learn more about scleroderma that were used in this video: Scleroderma Society of Ontario http://www.sclerodermaontario.ca/index.html Hamilton Scleroderma Group http://www.hamiltonscleroderma.org/ Additional References: Khanna, Dhanita. Diagnosis and treatment of systemic and localized scleroderma. Expert. Rev. Dermatol. 2011;6(3):287-302. Pope J, Johnson S. New Classification Criteria for Systemic Sclerosis (Scleroderma). Rheumatic Disease Clinics of North America. 2015;41(3):383-398.
Просмотров: 20690 Demystifying Medicine
An Overview of Scleroderma Part 3: Nutrition for Patients
 
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An Overview of Scleroderma Part 1: Breaking it Down http://www.youtube.com/watch?v=h6ti1eVo-9s An Overview of Scleroderma Part 2: Treatment and Management http://www.youtube.com/watch?v=6KLeGkeREkM Scleroderma is an autoimmune disease that involves the overproduction of collagen which results in the hardening, tightening and scarring of skin and internal organs. Several symptoms of scleroderma affect the digestive system, and as such, nutrition is an important component for patients. Although nutritional changes will not treat scleroderma, appropriate diets can reduce associated symptoms and improve quality of life. This video was created by McMaster Demystifying Medicine 4DM3 students: Helen Kim, Jessica Kun, Lyndsay Rayner, Nicole Vandenheuvel and Fadi Hana. Copyright McMaster University 2016 For more information: http://static1.squarespace.com/static/5280f5e9e4b0c046bfaad504/t/52dee1dce4b08b5d503210e7/1390338524898/SclerodermaNutrition.pdf http://www.scleroderma.org/site/DocServer/Eating_Well_with_Scleroderma.pdf?docID=1462
Просмотров: 5503 Demystifying Medicine
An Overview of Ultrasound Therapy
 
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This video gives a brief and simplified overview of Ultrasound therapy and its uses in Sports Medicine. This video was made by Hamza Khan in collaboration with the McMaster Demystifying Medicine Program. Copyright McMaster University 2017
Просмотров: 3767 Demystifying Medicine
What are Opioids?
 
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In this video presentation, we start by providing a basic understanding of opioids in terms of their origins and the major types available. From there, we go into a more details about what opioid overdose, addiction and physical dependence entails. The video then looks at why people take opioids, specifically looking at the use of opioids for the management of pain and the symptoms these drugs produce in the body. Finally, we look at the side effects of frequent opioid use and treatment options available for those with physical dependence or those experiencing an opioid overdose. This video was made by 4DM3 students Humaira Nakhuda, Tamandeep Khangura, Mateen Akhtar, Andrew Nashed and Vyshnavi Mahendran Please let us how you like this video and if you have any suggestions to how we can improve our videos. Copyright McMaster University 2016 References: Benyamin, R. et al. Opioid complications and side effects. Pain Physician. 2008;11(2):S105-20. Brownstein M. A brief history of opiates, opioid peptides, and opioid receptors. Proc Natl Acad Sci USA. 1993;90(12):5391. CAMH: Opioid Addiction [Internet]. Toronto (ON): CAMH; 2012 [cited 2016 Mar 8]. Available from: http://www.camh.ca/en/hospital/health_information/a_z_mental_health_and_addiction_information/Opioid-Dependence/Pages/default.aspx Canadian Centre on Substance Abuse [Internet].. Canadian drug summary: prescription opioids [Internet]. Canada: CCSA; 2015 [cited 2016 Nov 6]. Available from: http://www.ccsa.ca/Resource%20Library/CCSA-Canadian-Drug-Summary-Prescription-Opioids-2015-en.pdf Franklin G. Opioids for chronic noncancer pain: A position paper of the American Academy of Neurology. Neurology. 2014;83(14):1277-1284. Hilaire ML, Woods TM. Formulary Journal [Internet]. Ohio: Formulary Journal. Opioid abuse and dependence: treatment review and future options; 2010 Oct 1 [cited 2016 Mar 9]. Available from: http://formularyjournal.modernmedicine.com/formulary-journal/news/clinical/clinical-pharmacology/opioid-abuse-and-dependence-treatment-review-a?page=full Kosten TR, George TP. The neurobiology of opioid dependence: implications for treatment. Sci Pract Perspect. 2002 Jul;1(1):13–20. McCarberg BH, Barkin RL. Long-acting opioids for chronic pain: pharmacotherapeutic opportunities to enhance compliance, quality of life, and analgesia. Am J Ther.2001;8 (3);181-6. Rosenblum A, Marsch L, Joseph H, Portenoy R. Opioids and the treatment of chronic pain: Controversies, current status, and future directions. Exp Clin Psychopharm. 2008;16(5):405-16. World Health Organization. Information sheet on opioid overdose [Internet]. WHO; 2014 [cited 2016 Nov 6]. Available from: http://www.who.int/substance_abuse/information-sheet/en/
Просмотров: 3552 Demystifying Medicine
The Super Sepsis Six
 
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This video discusses the diagnostic and treatment processes that should be conducted within the first hour when a patient comes into a hospital with sepsis. This video was created by McMaster Demystifying Medicine 4DM3 students Kirat Boparai, Breagh Cheng, Mankeeran Dhanoa and Anjali Periyalwar Copyright McMaster University 2016 References: 1. Health Canada. Deaths Involving Sepsis in Canada, 2016. Retreived from http://www.statcan.gc.ca/pub/82-624-x/2016001/article/14308-eng.htm 2. 2) Bone, C.; Balk, A.; Cerra, B.; Dellinger, P.; Fein, M.; Knaus, A.; Sibbald, J. Chest Journal. 1992, 101(6), 1644-1655. 3. Levy, M.; Fink, P.; Marshall, C.; Abraham, E.; Angus, D.; Cook, D.; Ramsay, G. Intensive care medicine. 2003, 29(4), 530-538. 4. Daniels, R.; Nutbeam, T.; McNamara, G.; Galvin, C. Emergency Medicine Journal. 2011, 28(6), 507-512. 5. Daniels, R. (2011). Surviving the first hours in sepsis: getting the basics right (an intensivist's perspective). J. Antimicrob. Chemother.  66 (2), ii11-ii23. 6. Chang, R., & Holcomb, J. B. (2016). Choice of Fluid Therapy in the Initial Management of Sepsis, Severe Sepsis, and Septic Shock. Shock (Augusta, Ga.). 7. Semler, M. W., & Rice, T. W. (2016). Sepsis Resuscitation: Fluid Choice and Dose. Clinics in Chest Medicine. 8. Chen, L. (2016). Don't Go Chasing Waterfalls: Excessive Fluid Resuscitation in Severe Sepsis and Septic Shock. Critical care nursing quarterly, 39(1), 34-37. 9. Gauer, R. L. (2013). Early recognition and management of sepsis in adults: the first six hours. American family physician, 88(1) 10. http://bestpractice.bmj.com/best-practice/monograph/245/treatment/step-by-step.html 11. Leone, M.; Bourgoin, A.; Cambon, S.; Dubuc, M.; Albanèse, J.; Martin, C. Crit. Care Med. 2003, 31 (2), 462–467. 12. Leibovici, L.; Shraga, I.; Drucker, M.; Konigsberger, H.; Samra, Z.; Pitlik, S. D. J. Intern. Med. 1998, 244, 379–386. 13. Garnacho-Montero, J.; Garcia-Garmendia, J. L.; Barrero-Almodovar, A.; Jimenez-Jimenez, F. J.; Perez-Paredes, C.; Ortiz-Leyba, C. Crit. Care Med. 2003, 31 (12), 2742–2751. 14. Bochud, P.-Y.; Bonten, M.; Marchetti, O.; Calandra, T. Crit. Care Med. 2004, 32 (11), S495–S512. Canadian Association of Emergency Physicians. Canadian Association of Emergency Physician Sepsis Guidelines.
Просмотров: 20856 Demystifying Medicine
What is Sleep Paralysis?
 
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Sleep paralysis can be a scary experience, but this video is here to help clear some of the fear and confusion surrounding the strange phenomenon. The video explores what sleep paralysis really is, its biological cause, and also presents some tips to help prevent sleep paralysis. This video was created by Demystifying Medicine students Minahil Jabeen, Dhruvika Joshi, Prabhjot Khabra and Vanessa Lombardo. Copyright McMaster University 2017 References: Denis, D., French, C., & Gregory, A. (2017). A systematic review of variables associated with sleep paralysis. Sleep Medicine Reviews. http://dx.doi.org/10.1016/j.smrv.2017.05.005 Denis, D., French, C. C., Rowe, R., Zavos, H., Nolan, P. M., Parsons, M. J., & Gregory, A. M. (2015). A twin and molecular genetics study of sleep paralysis and associated factors. Journal of sleep research, 24(4), 438-446. Fukuda, K. (2005). Emotions during sleep paralysis and dreaming. Sleep And Biological Rhythms, 3(3), 166-168. http://dx.doi.org/10.1111/j.1479-8425.2005.00172.x Golzari, S., Khodadoust, K., Alakbarli, F., Ghabili, K., Islambulchilar, Z., & Shoja, M. et al. (2012). Sleep paralysis in medieval Persia - the Hidayat of Akhawayni (?-983 AD). Neuropsychiatric Disease and Treatment, 229-234. http://dx.doi.org/10.2147/ndt.s28231 Guilleminault C., and Fromherz S.: Narcolepsy: diagnosis and management. In Kryger M.H., Roth T., and Dement W.C. (eds): Principles and practice of sleep medicine, 4th edition. Philadelphia (PA): Elsevier Saunders, 2005. pp. 780-790 Kompanje, E. (2008). ‘The devil lay upon her and held her down’Hypnagogic hallucinations and sleep paralysis described by the Dutch physician Isbrand van Diemerbroeck (1609-1674) in 1664. Journal of Sleep Research, 17(4), 464-467. http://dx.doi.org/10.1111/j.1365-2869.2008.00672.x Lu, J., Sherman, D., Devor, M., & Saper, C. (2006). A putative flip–flop switch for control of REM sleep. Nature, 441(7093), 589-594. http://dx.doi.org/10.1038/nature04767 National Institutes of Health. (2017). What is REM sleep?. Eunice Kennedy Shriver National Institute of Child Health and Human Development. Retrieved 7 November 2017, from https://www.nichd.nih.gov/health/topics/sleep/conditioninfo/Pages/rem-sleep.aspx#top Ohayon, M., Priest, R., Caulet, M., & Guilleminault, C. (1996). Hypnagogic and hypnopompic hallucinations: pathological phenomena?. The British Journal Of Psychiatry, 169(4), 459-467. http://dx.doi.org/10.1192/bjp.169.4.459 Ohayon M.M., Zulley J., Guilleminault C., et al: Prevalence and pathologic associations of sleep paralysis in the general population. Neurology 1999; 52: pp. 1194-1200 Plante, D. T., & Winkelman, J. W. (2008). Parasomnias: psychiatric considerations. Sleep Medicine Clinics, 3(2), 217-229. Sharpless, B., & Barber, J. (2011). Lifetime prevalence rates of sleep paralysis: A systematic review. Sleep Medicine Reviews, 15(5), 311-315. http://dx.doi.org/10.1016/j.smrv.2011.01.007 Sharpless, B. A., & Grom, J. L. (2014). Isolated Sleep Paralysis: Fear, Prevention, and Disruption. Behavioral Sleep Medicine, 1–6. doi:10.1080/15402002.2014.963583 Solomonova, E. (2017). Sleep Paralysis: phenomenology, neurophysiology and treatment. In The Oxford Handbook of Spontaneous Thought: Mind-Wandering, Creativity, Dreaming, and Clinical Conditions. Oxford University Press. Editors: Kieran Fox, Kalina Christoff
Просмотров: 14472 Demystifying Medicine
Living with Generalized Anxiety Disorder
 
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Ever wondered what it’s like for someone with GAD to go about their day? Maybe you know someone with GAD, but do you really know what their thoughts and emotions are? If you don't have GAD, it can be hard to understand what it feels like. This video will take you through the inner thoughts of someone with this anxiety disorder, and then transition into causes, prevalence rates and treatment options. This video was made by McMaster Demystifying Medicine students Sandra Yousif, Hajer Nakua, Nimi Patel and Nivy Pattathil Copyright McMaster University 2018 References: Reynolds, C. R., & Kamphaus, R. W. (Eds.). (2003). Handbook of psychological and educational assessment of children: Personality, behavior, and context (Vol. 2). Guilford Press. Section B - Anxiety disorders. (2015, November 27). Retrieved March 02, 2018, from http://www.statcan.gc.ca/pub/82-619-m/2012004/sections/sectionb-eng.htm#a4 Anxiety Disorders Association of Canada. (n.d.). Retrieved March 02, 2018, from http://www.anxietycanada.ca/english/index.php World Health Organization. (2017). Depression and other common mental disorders: global health estimates. Kadam, U. T., Croft, P., McLeod, J., & Hutchinson, M. (2001). A qualitative study of patients' views on anxiety and depression. Br J Gen Pract, 51(466), 375-380. Hjeltnes, A., Binder, P. E., Moltu, C., & Dundas, I. (2015). Facing the fear of failure: An explorative qualitative study of client experiences in a mindfulness-based stress reduction program for university students with academic evaluation anxiety. International journal of qualitative studies on health and well-being, 10(1), 27990. Craske, M. G., Rapee, R. M., Jackel, L., & Barlow, D. H. (1989). Qualitative dimensions of worry in DSM-III-R generalized anxiety disorder subjects and nonanxious controls. Behaviour Research and Therapy, 27(4), 397-402.
Просмотров: 6170 Demystifying Medicine
Your Brain on Social Anxiety Disorder
 
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Social anxiety disorder (S.A.D.) is characterized by a chronic uncontrollable fear stemming from social situations. People with social anxiety disorder may feel fear from being around a group of people, from one on one encounters, or even from imagining being around others. This disorder leads to social isolation and avoidance. You might be wondering what is happening within the brain of someone with S.A.D. Watch this video to learn about some of the brain structures associated with this disorder and what they do. This video was created by McMaster Demystifying Medicine 4DM3 students Annelise Kohler, Fangyi (Fanny) Liu, Zion Lee, Eshan Shah and Rafaella Shamans. Copyright McMaster University 2015. Here are links to the resources discussed in the video: Mood Disorders Society of Canada Website à http://www.mooddisorderscanada.ca/ McMaster Student Wellness Centre Website à http://wellness.mcmaster.ca/
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What is a Spinal Cord Injury?
 
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This video presents an overview of spinal cord injuries and research. It covers the epidemiology, causes, symptoms, treatments and cures for spinal cord injuries. It looks at the future of spinal cord injury research. Video by Manveer Singh, Emma Hudson, Patricia Kitala and Shahriar Ameri Copyright McMaster University 2017 References Signs & Symtoms of Spinal Cord Injuries | SpinalCord.com [Internet]. Spinalcord.com. 2017 [cited 12 March 2017]. Available from: http://www.spinalcord.com/signs-symtoms-of-spinal-cord-injuries Kadoya K, Lu P, Nguyen K, Lee-Kubli C, Kumamaru H, Yao L et al. Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration. Nature Medicine. 2016;22(5):479-487. Chen Y, Tang Y, Vogel L, DeVivo M. Causes of Spinal Cord Injury. Topics in Spinal Cord Injury Rehabilitation. 2013;19(1):1-8. What are the treatments for spinal cord injury (SCI)? [Internet]. National Institute of Child Health and Human Development. 2017 [cited 13 March 2017]. Available from: https://www.nichd.nih.gov/health/topics/spinalinjury/conditioninfo/Pages/treatments.aspx Angeli C, Edgerton V, Gerasimenko Y, Harkema S. Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans. Brain. 2014;137(5):1394-1409. Schmidt E. Experimental implant shows promise for restoring voluntary movement after spinal cord injury [Internet]. UCLA Newsroom. 2017 [cited 13 March 2017]. Available from: http://newsroom.ucla.edu/releases/experimental-implant-shows-promise-for-restoring-voluntary-movement-after-spinal-cord-injury White, N. H., & Black, N. H. (2016). Spinal cord injury (SCI) facts and figures at a glance. Available from: https://www.nscisc.uab.edu/Public/Facts%202016.pdf Spinal cord injury. (n.d.). Retrieved March 13, 2017, from http://www.mayoclinic.org/diseases-conditions/spinal-cord-injury/basics/definition/con-20023837
Просмотров: 58681 Demystifying Medicine
Hemodialysis (in Urdu)
 
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This video outlines a basic overview of Hemodialysis and the steps of the procedure in urdu. This video is meant only to educate patients about the benefits of Hemodialysis and answer questions about the process. 1 in 10 American adults and more than 2 million have chronic kidney disease. Hemodialysis is currently an effective alternative for healthy functioning kidneys and has allowed others with kidney failure to filter blood. This video was made by Hamza Khan (McMaster Undergraduate Student) and Yusra Khan in collaboration with the McMaster Demystifying Medicine Program. Special thanks to Yusra Khan for script editing. Please let us know how we can improve our videos and which questions should be developed below. Copyright McMaster University 2016
Просмотров: 5947 Demystifying Medicine
Developmental Origins of Health and Disease (DOHaD)
 
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Many people do not know that genetic changes occur in response to environmental factors—even as early as a fetus. This video discusses the role of long lasting epigenetic effects related to poor nutrient environment for the fetus, and the first DoHaD study looking at obesity rates related to the Dutch Famine of 1944-1945. This video was made by 4DM3 students Akshay Venkatesh, Cindy Li, Archita Srinath, Haider Abed and Kyra Posterski. Copyright McMaster University 2016 References Schulz, L. C. (2010). The Dutch Hunger Winter and the developmental origins of health and disease. Proceedings of the National Academy of Sciences , 107 (39), 16757—16758. Reynolds, L. P., Borowicz, P. P., Caton, J. S., Vonnahme, K. A., Luther, J. S., Hammer, C. J., & Redmer, D. A. (2010). Developmental programming: the concept, large animal models, and the key role of uteroplacental vascular development. Journal of animal science , 88 (13), E61—E72. Silveira, P. P., Portella, A. K., Goldani, M. Z., & Barbieri, M. A. (2007). Developmental origins of health and disease (DOHaD). Jornal de pediatria , 83 (6), 494—504.
Просмотров: 4987 Demystifying Medicine
Corneal Transplant Surgery: A Patient Information Video
 
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Since the first successful corneal transplant surgery in 1905, this operation has become a critical tool in ophthalmology. This video explains the corneal transplantation operation to help patients understand what they can expect after the surgery in terms of possible complications and standard care. This video was created by a group of McMaster University students in a knowledge translation course for the Demystifying Medicine series: Verina Hanna, Michelle Goldsand, Angie Ibrahim, Bakht Khan, and Ramneet Mann. Please let us know how we can improve our videos and suggest topics to demystify below. Copyright McMaster University 2016 References Moffatt SL, Cartwright VA, Stumpf TH. Centennial review of corneal transplantation. Clinical & Experimental Ophthalmology. 2005 Dec 1;33(6):642–57. Panda A, Vanathi M, Kumar A, Dash Y, Priya S. Corneal graft rejection. Surv Ophthalmol. 2007 Aug;52(4):375–96. Tan DT, Dart JK, Holland EJ, Kinoshita S. Corneal transplantation. The Lancet. 2012 May 11;379(9827):1749–61. What Are Corneal Dystrophies? [Internet]. American Academy of Ophthalmology. 2015 [cited 2016 Oct 30]. Available from: http://www.aao.org/eye-health/diseases/corneal-dystrophies "Anatomy Of The Eye — AAPOS". American Association for Pediatric Ophthalmology and Strabismus. N.p., 2016. Web. 30 Oct. 2016. "Corneal Transplants". CLEI Center for Keratoconus. N.p., 2016. Web. 30 Oct. 2016.
Просмотров: 8962 Demystifying Medicine
What is Multiple Sclerosis (MS)?
 
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This video presents an overview of multiple sclerosis (MS) and current reaearch. Many people in the world are affected by multiple sclerosis (MS), but what exactly is MS? MS is a demyelinating autoimmune disease that attacks the protective covering of the nerves in the brain and spinal cord, which can lead to various symptoms. While most forms of MS are now very manageable with advances in medicine, more research is needed to find a cure. Video by Emma Hudson, Patricia Kitala, Manveer Singh, Shahriar Ameri Copyright McMaster University 2017 Please let us know below how you liked this video and suggest additional topics for us to attempt to demystify. References: Compston, Alastair, H. Lassmann, and I. McDonald. "The story of multiple sclerosis." McAlpine‘s Multiple Sclerosis. 3rd ed. London: Churchill Livingstone (1998). IFNB Multiple Sclerosis Study Group. "Interferon beta‐1b is effective in relapsing‐remitting multiple sclerosis I. Clinical results of a multicenter, randomized, double‐blind, placebo-controlled trial." Neurology 43, no. 4 (1993): 655-655. Kappos, Ludwig, Ernst-Wilhelm Radue, Paul O'connor, Chris Polman, Reinhard Hohlfeld, Peter Calabresi, Krzysztof Selmaj et al. "A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis." New England Journal of Medicine 362, no. 5 (2010): 387-401. La Mantia, Loredana, Luca M. Munari, and Roberta Lovati. "Glatiramer acetate for multiple sclerosis." The Cochrane Library (2010). Orton, Sarah-Michelle, Blanca M. Herrera, Irene M. Yee, William Valdar, Sreeram V. Ramagopalan, A. Dessa Sadovnick, George C. Ebers, and Canadian Collaborative Study Group. "Sex ratio of multiple sclerosis in Canada: a longitudinal study." The Lancet Neurology 5, no. 11 (2006): 932-936.
Просмотров: 2115 Demystifying Medicine
Idiopathic Pulmonary Fibrosis (IPF): Risk Factors and Diagnosis
 
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Explains the risk factors and diagnosis involved with Idiopathic Pulmonary Fibrosis (IPF).
Просмотров: 4917 Demystifying Medicine
Music Therapy for Autism Spectrum Disorder
 
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This video explores music therapy as a treatment for autism spectrum disorder (ASD). Music is used to address physical, emotional, cognitive and social needs of the person who has ASD. Treatment is provided through singing, dancing, listening or even creating music. Video by Health Sciences students Curtis Menon, Jenna Price, Yousif Eliya and Balpreet Panesar. Copyright McMaster University 2017 References: Autism Spectrum Disorder: Communication Problems in Children. (2017). NIDCD. Retrieved 16 November 2017, from https://www.nidcd.nih.gov/health/autism-spectrum-disorder-communication-problems-children Challenges for ASD. Autism Community. Retrieved 16 November 2017, from http://www.autism-community.com/communication/challenges-for-asd/ Data & Statistics. (2017). Cdc.gov. Retrieved 16 November 2017, from https://www.cdc.gov/ncbddd/autism/data.html Mulligan, J., MacCulloch, R., Roberts, W., & Steel, L. (2017). What Is Autism Spectrum Disorder?. Aboutkidshealth.ca. Retrieved 16 November 2017, from http://www.aboutkidshealth.ca/En/ResourceCentres/AutismSpectrumDisorder/WhatisASD/Pages/default.aspx Music Therapy. (2016). Autism Canada. Retrieved 16 November 2017, from https://autismcanada.org/living-with-autism/treatments/related/music-therapy/ Mössler, K., Gold, C., Aßmus, J., Schumacher, K., Calvet, C., Reimer, S., ... & Schmid, W. (2017). The Therapeutic Relationship as Predictor of Change in Music Therapy with Young Children with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 1-15. McLaurin-Jones, T., Odogwu, C., Brooks, B., & Egu-Okoronkwo, N. (2017). Can music therapy improve social interaction and verbal communication in individuals with autism spectrum disorder? Evidence-based practice 20, no. 4 (2017): E8 https://mospace.umsystem.edu/xmlui/bitstream/handle/10355/60151/EBP-201704-24.pdf?sequence=1&isAllowed=y
Просмотров: 3584 Demystifying Medicine
Demystifying Dystonia
 
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In this video presentation, we start by providing a basic overview of what dystonia is and the prevalence of this condition by looking at both age and gender. Afterwards, a discussion on the components of the brain that dystonia is usually linked to is discussed in order to give insight into how dystonia affects the stimulation and causes the excessive contraction of the muscle or muscle group it affects. In the presentation the various ways that could cause dystonia are also looked at so that the audience that is watching the video has some background information about that. A quick glance of the different types of dystonia as well as the symptoms of this condition were also mentioned to give insight to this common, yet rarely talked about, condition is all about. Towards the end of the video a more in depth discussion on the various forms of treatment such Botox injections, anticholinergic medication, and deep brain stimulation surgery were discussed and how they differ from each other and when to use which depending on the severity of the condition and the resources available. Neurotransmitters such as acetylcholine were discussed and their role in the body by innervating the muscle in order to contract. The video also explained complex genetic concepts related to the cause of Dystonia as well as the main components of the brain that is affected by this condition in order to make the video an enjoyable learning experience for all ages who are going to view the video. This video was made by 4DM3 students Vyshnavi Mahendran, Tamandeep Khangura, Humaira Nakhuda, Mateen Akhtar and Andrew Nashed. Please let us how you like this video and if you have any suggestions to how we can improve our videos. Copyright McMaster University 2016 References: Meadows AA of NS 5550 MD-R. The American Association of Neurological Surgeons [Internet]. [cited 2016 Oct 30]. Available from: https://www.aans.org Richter A, Löscher W. Pathophysiology of idiopathic dystonia: findings from genetic animal models. Progress in Neurobiology. 1998 Apr 24;54(6):633–77. Available from: http://www.sciencedirect.com/science/article/pii/S0301008297000890 Purves D, Augustine GJ, Fitzpatrick D, Katz LC, LaMantia A-S, McNamara JO, et al. Acetylcholine. 2001 [cited 2016 Oct 30]; Available from: https://www.ncbi.nlm.nih.gov/books/NBK11143/ Dystonia [Internet]. [cited 2016 Oct 30]. Available from: https://medlineplus.gov/dystonia.html
Просмотров: 4746 Demystifying Medicine
Antioxidants & Aging: A Radical Theory
 
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A common misconception that has been circulating for many years is the role of antioxidants in the body and their implication. This video examines the process of aging and the role of antioxidants and free radicals in the body.s on aging. Video by Erika Opingari, Brenton Wong, Coomal Rashid, Healey Schulman and Kavena Sivakumar Please let us how you like this video and if you have any suggestions to how we can improve our videos. Copyright McMaster University 2016 References: Scudellari M. The science myths that will not die. Nature. 2015 Dec 16;528(7582):322–5. Pham-Huy LA, He H, Pham-Huy C. Free Radicals, Antioxidants in Disease and Health. Int J Biomed Sci. 2008;4(2):89–96. Lobo V, Patil A, Phatak A, Chandra N. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacogn Rev. 2010;4(8):118. Devasagayam T, Tilak J, Boloor K, Sane K, Ghaskadbi S, Lele R. Free Radicals and Antioxidants in Human Health: Current Status and Future Prospects. Journal of the Association of Physicians of India [Internet]. 2004 Oct [cited 2016 Oct 10];52. Available from:https://www.researchgate.net/profile/Saroj_Ghaskadbi/publication/7831516_Free_Radicals_and_Antioxidants_in_Human_Health_Current_Status_and_Future_Prospects/links/56ef793b08ae4b8b5e756f2f.pdf Finkel T. Signal transduction by reactive oxygen species. The Journal of cell biology. 2011 Jul 11;194(1):7-15. Van Raamsdonk JM, Hekimi S. Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans. PLoS Genet. 2009 Feb 6;5(2):e1000361. Sanz A, Stefanatos RK. The mitochondrial free radical theory of aging: a critical view. Current aging science. 2008 Mar 1;1(1):10-21. Aging NI on. What is aging? [Internet]. National Institute on Aging. 2011. Available from:https://www.nia.nih.gov/health/publication/aging-under-microscope/what-aging Shammas MA. Telomeres, lifestyle, cancer, and aging. Current opinion in clinical nutrition and metabolic care. 2011 Jan;14(1):28. Rafieian-Kopaei M, Baradaran A, Rafieian M. Oxidative stress and the paradoxical effects of antioxidants. Journal of Research in Medical Sciences. 2013 Jul 11;18(7):628.
Просмотров: 4860 Demystifying Medicine
Motor Rehabilitation after Stroke
 
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Our video demystifies a review paper addressing motor rehabilitation in stroke survivors and using an aerobic exercise intervention protocol to increase levels of brain-derived neurotrophic factor (BDNF) and optimize results of motor training. This video was made by Jenin El-Sayes, Jonathan Ho, Dil Prabaharan, Arun Ravikumar and Shan Tandon Copyright McMaster University 2016 References Mang, et al. 2013. Promoting Neuroplasticity for Motor Rehabilitation after Stroke: Considering the Effects of Aerobic Exercise and Genetic Variation on Brain-Derived Neurotrophic Factor. Physical Therapy.. 93 (12) p.1707-1716. Knaepen K., Goekint M., Heyman F.M., & Meeusen R. 2010. Neuroplasticity exercise-induced response of peripheral brain-derived neurotrophic factor: a systematic review of experimental studies in human subjects. Sports Med. 40 p. 765-801 Pang M., Charlesworth S., Lau R., & Chung R. 2013. Using Aerobic Exercise to Improve Health Outcomes and Quality of Life in Stroke: Evidence-Based Exercise Prescription Recommendations. Cerebrovasc Dis, 35(1) p. 7-22. http://dx.doi.org/10.1159/000346075 Stroke Report 2014: Together against a Rising Tide. Heart and Stroke Foundation. 2014:1-14. O'Sullivan S. 2004. Stroke. In: O'Sullivan, S.B., and Schmitz, T.J. Physical Rehabilitation. Philadelphia, PA: F.A. Davis Company; 5 p.719. Quaney B.M., Boyd L.A,, McDowd J.M., et al. 2009. Aerobic exercise improves cognition and motor function poststroke. Neurorehabil Neural Repair. 23 p. 879–885
Просмотров: 4478 Demystifying Medicine
Obsessive-Compulsive Disorder - Through My Eyes
 
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Go through a typical day of a person with obsessive compulsive disorder (OCD). This video is based on a personal account and demonstrates habits, behaviours and thoughts that a person with OCD may experience. The behaviours and rituals depicted are not common to everyone with OCD but specific to each individual. If you have OCD, or if you know someone who does, the following resources may be of help: Anxiety Disorders Association of Canada: http://www.anxietycanada.ca Association for Behavioural and Cognitive Therapies: http://www.abct.org International OCD Foundation: https://iocdf.org The International OCD Foundation is a good place to start to find help. On the home page look for the section with the title "Find Help." Below the title is a place where you can search for resources available in your location. Enter your location and click "Find." There is professional help available. Centre for Addiction and Mental Health (CAMH): http://www.camh.ca This video was made by Health Science 4DM3 students Saima Ahmad, Atherai Maran, Candy Niu, and Joy Sumin Park. Copyright McMaster University 2017
Просмотров: 24070 Demystifying Medicine
Scleroderma Renal Crisis
 
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This video is an introduction to Scleroderma Renal Crisis, a very rare yet dangerous complication of Scleroderma, an autoimmune disease that affects the skin and internal organs. The video was developed by HTH SCI 4DM3 students Sarah Gabrial, Hussain Abbas, Renuka Singh, Justin Wu and Aaron Edward. Copyright McMaster University 2016 References Bose, N., Chiesa-Vottero, A., & Chatterjee, S. (2015, June). Scleroderma renal crisis. In Seminars in arthritis and rheumatism (Vol. 44, No. 6, pp. 687-694). WB Saunders. Bussone, G., Bérezné, A., Pestre, V., Guillevin, L., & Mouthon, L. (2011). The scleroderma kidney: progress in risk factors, therapy, and prevention. Current rheumatology reports, 13(1), 37-43. Campbell, P. M., & LeRoy, E. C. (1975, May). Pathogenesis of systemic sclerosis: a vascular hypothesis. In Seminars in arthritis and rheumatism (Vol. 4, No. 4, pp. 351-368). WB Saunders. Fox, R. (2005). What is Scleroderma Renal Crisis and How Is It Managed?. WebMD. Retrieved from http://www.medscape.com/viewarticle/507319 Ostojić, P., & Damjanov, N. (2006). Different clinical features in patients with limited and diffuse cutaneous systemic sclerosis. Clinical rheumatology,25(4), 453-457. Penn, H., & Denton, C. P. (2008). Diagnosis, management and prevention of scleroderma renal disease. Current opinion in rheumatology, 20(6), 692-696. Rhew, E. Y., & Barr, W. G. (2004). Scleroderma renal crisis: new insights and developments. Current rheumatology reports, 6(2), 129-136.
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What Is a Pulmonary Embolism?
 
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This video defines what a pulmonary embolism (PE) is and then goes over what happens in the body during a pulmonary embolism. It discusses risk factors, signs and symptoms, diagnosis and prevention and treatment. Since PE can be a fatal condition, it is important that individuals know what to look for so that they, or their loved ones, seek proper medical attention. This video was made by McMaster Demystifying Medicine students Andy Fensham, Angela Gupta, Navi (Harmandeep) Dhaliwal and Viktoriya Dyubanova. Copyright McMaster University 2017 References: 1. Goldhaber S, Bounameaux H. Pulmonary embolism and deep vein thrombosis. The Lancet. 2012;379(9828):1835-1846. 2. Bĕlohlávek J, Dytrych V, Linhart A. Pulmonary embolism, part I: Epidemiology, risk factors and risk stratification, pathophysiology, clinical presentation, diagnosis and nonthrombotic pulmonary embolism. Experimental & Clinical Cardiology. 2013;18(2):129-138. 3. National Heart, Lung, and Blood Institute. What is pulmonary embolism [Internet]. National Institute of Health: Department of Health and Human Services; 2011 July 1 [cited 2017 Oct 15]. Available from: https://nhlbi.nih.gov/health/health-topics/topics/pe 4. Mayo Clinic. Pulmonary embolism [Internet]. Mayo Foundation for Medical Education and Research: Mayo Clinic Staff; 2017 Aug 17 [cited 2017 Oct 15]. Available from: https://www.mayoclinic.org/diseases-conditions/pulmonary-embolism/symptoms-causes/syc-20354647 5. Heit JA, Silverstein MD, Mohr DN, Petterson TM, O'fallon WM, Melton LJ. Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study. Archives of Internal Medicine. 2000 Mar 27;160(6):809-15. 6. Coon WW, Coller FA. Some epidemiologic considerations of thromboembolism. Surgery, Gynecology & Obstetrics. 1959 Oct;109:487-501. 7. Quinn DA, Thompson BT, Terrin ML, Thrall JH, Athanasoulis CA, McKusick KA, Stein PD, Hales CA. A prospective investigation of pulmonary embolism in women and men. JAMA. 1992 Oct 7;268(13):1689-96. 8. Gibbs NM. Venous thrombosis of the lower limbs with particular reference to bed‐rest. British Journal of Surgery. 1957 Nov 1;45(191):209-36. 9. Gross JS, Neufeld RR, Libow LS, Gerber I, Rodstein M. Autopsy study of the elderly institutionalized patient: review of 234 autopsies. Archives of Internal Medicine. 1988 Jan 1;148(1):173-6. 10. Goldhaber SZ, Grodstein F, Stampfer MJ, Manson JE, Colditz GA, Speizer FE, Willett WC, Hennekens CH. A prospective study of risk factors for pulmonary embolism in women. JAMA. 1997 Feb 26;277(8):642-5. 11. Goldhaber SZ, Savage DD, Garrison RJ, Castelli WP, Kannel WB, McNamara PM, Gherardi G, Feinleib M. Risk factors for pulmonary embolism: the Framingham Study. The American Journal of Medicine. 1983 Jun 1;74(6):1023-8. 12. Smeeth L, Cook C, Thomas S, Hall AJ, Hubbard R, Vallance P. Risk of deep vein thrombosis and pulmonary embolism after acute infection in a community setting. The Lancet. 2006 Apr 7;367(9516):1075-9. 13. Virchow RLK. Thrombose und embolie [Thrombosis and emboli]. Massachusetts: Science History Publications, 1998. 14. Chung J, Owen R. Using inferior vena cava filters to prevent pulmonary embolism. Canadian Family Physician. 2008 Jan; 54(1): 49-55.
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Lung Cancer: Staging Presentation
 
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McMaster Demystifying Medicine 4DM3 Students Mardin Ali, Rupali Patel, Cory Richman and John Sawires present here a video explaining the different types of lung cancer and how staging is typically performed. Copyright McMaster University 2014 Please let us know how you liked this video and suggest additional topics to be demystified below.
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Ketogenic diet as a method of treatment for epilepsy
 
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This video examines the research and scientific information surrounding the benefits a ketogenic diet can have for individuals that may be suffering from epilepsy. It also considers the potential healthcare benefits of the ketogenic diet with respect to children who suffer from recurring epilepsy. This video was made by Health Science 4DM3 students: Melika Babadi, Babur Ali, Mohammed Abdul-Khaliq and Shamweel Arman Copyright McMaster University 2018 References: Gilmour, H., Ramage-Morin, P., & Wong, S. L. (2016). Epilepsy in Canada: Prevalence and impact. Health Reports, 27(9), 24. Kim, D. Y., & Rho, J. M. (2008). The ketogenic diet and epilepsy. Current Opinion in Clinical Nutrition and Metabolic Care, 11(2), 113-120. Schwartz, R. M., Boyes, S., & Aynsley‐Green, A. (1989). Metabolic effects of three ketogenic diets in the treatment of severe epilepsy. Developmental Medicine and Child Neurology, 31(2), 152-160. Gilbert, D. L., Pyzik, P. L., & Freeman, J. M. (2000). The ketogenic diet: seizure control correlates better with serum β-hydroxybutyrate than with urine ketones. Journal of Child Neurology, 15(12), 787-790. Huttenlocher, P. R. (1976). Ketonemia and seizures: metabolic and anticonvulsant effects of two ketogenic diets in childhood epilepsy. Pediatric Research, 10(5), 536.
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How is sepsis treated? Sepsis 6 Demystified
 
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SIRS, Systemic Inflammatory Response Syndrome (SIRS) is also known as Sepsis. Sepsis is the most frequent cause of mortality in intensive care units (ICUs) and is responsible for more than 250,000 deaths in the United States annually. This video aims to spread awareness regarding sepsis and help people understand the current treatments in place to treat it. Sepsis 6 consists of three diagnostic and three therapeutic steps which are currently being used as guidelines of sepsis treatment within hospitals. This video was created by McMaster Demystifying Medicine 4DM3 students: Helen Kim Jessica Kun, Lyndsay Rayner, Nicole Vandenheuvel and Fadi Hana. Copyright McMaster University 2016
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A to Z of the Fight or Flight Response
 
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This video is an infographic describing the fight or flight response in humans when faced by a threat. It describes the stress response associated with cortisol and the fight or flight response associated with adrenaline. The video explains how a stimulus is perceived, how the brain processes information, the messages sent to the body and the physiological changes in preparation for the response. This video was made by Health Science 4DM3 students Khaled Nawar, Victoria Claggett, Cayla Lenefesty and Tiffany Sun. Copyright McMaster University 2017. Please let us know how you liked this video and suggest additional topics for us to demystify below. References : Goldstein, D. S. (2010). Adrenal Responses to Stress. Cellular and Molecular Neurobiology, 30(8), 1433–1440. http://doi.org/10.1007/s10571-010-9606-9 Harvard University. (2011). Understanding the stress response. Harvard Health Publishing. Retrieved from https://www.health.harvard.edu/staying-healthy/understanding-the-stress-response Jansen, A., Nguyen, X., Karpitskiy, V., Mettenleiter, T., & Loewy, A. (1995). Central command neurons of the sympathetic nervous system: Basis of the fight-or-flight response. Science, 270 (5236). McEwen, B. (2005). Stressed or stressed out: what is the difference? Journal of Psychiatry and Neuroscience, 30. Steimer, T. (2002). The biology of fear- and anxiety-related behaviors. Dialogues in Clinical Neuroscience, 4(3), 231–249.
Просмотров: 7878 Demystifying Medicine
Break a Leg: Stress Fractures
 
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This video (styled as a vlog) details the accounts of a runner who was diagnosed with a stress fracture. An overview of stress fractures is given, followed by diagnosis methods and related challenges. The target audience for this video is physically active people, especially teens and young adults. This video was made by McMaster University Demystifying Medicine students Sandra Yousif, Rana Ghafouri, Ally Di Iorio and Varsha Jayansakar Copyright McMaster University 2017 References: Boden, B. P., & Osbahr, D. C. (2000). High‐risk stress fractures: evaluation and treatment. Journal of the American Academy of Orthopaedic Surgeons, 8(6), 344-353. Daffner, R. H., & Pavlov, H. (1992). Stress fractures: current concepts. AJR. American journal of roentgenology, 159(2), 245-252. Milgrom, C., Chisin, R., Giladi, M., Stein, M., Kashtan, H., Margulies, J., & Atlan, H. (1984). Negative bone scans in impending tibial stress fractures: a report of three cases. The American journal of sports medicine, 12(6), 488-491. Myburgh, K. H., Hutchins, J., Fataar, A. B., Hough, S. F., & Noakes, T. D. (1990). Low bone density is an etiologic factor for stress fractures in athletes. Annals of internal medicine, 113(10), 754-759. Patel, D. S., Roth, M., & Kapil, N. (2011). Stress fractures: diagnosis, treatment, and prevention. Am Fam Physician, 83(1), 39-46. Schneiders, A. G., Sullivan, S. J., Hendrick, P. A., Hones, B. D., McMaster, A. R., Sugden, B. A., & Tomlinson, C. (2012). The ability of clinical tests to diagnose stress fractures: a systematic review and meta-analysis. journal of orthopaedic & sports physical therapy, 42(9), 760-771.
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GERD: Symptoms and Treatments
 
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This video presents an overview of gastroesophageal reflux disease and describes the symptoms and treatments of the condition.  Video by high school students at Hillfield Strathallan College
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Demystifying Post-Traumatic Stress Disorder (PTSD)
 
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Have you ever wondered what PTSD stands for? About who is affected by this debilitating condition? Or how people cope with it and current treatment options? If so, this video will provide a brief overview causes, symptoms, prevalence, diagnosis and therapeutic treatment of PTSD. Video and animation content were taken from the following youtube videos: Understanding PTSD: Gina's story - https://www.youtube.com/watch?v=nZLD9z6_bFI How Prozac works- brief animation - http://www.youtube.com/watch?v=ocSptPUBbuo&feature=youtu.be PTSD - Post Traumatic Stress Disorder - http://www.youtube.com/watch?v=c-jq36RKVa8 Produced by HTH SCI 4DM3 students: Christopher Chiang, Alon Coret, Yalda Karimi, Babak Nouhi, and Warren Viegas
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Action of Breathing — Part 1: Mechanisms
 
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An overview of the muscles involved in breathing, and their associated mechanisms. The presentation is divided into 2 main sections - inspiration and expiration with both sections further divided into active and passive breathing. This video was created by a group of McMaster University students in a knowledge translation course for the Demystifying Medicine series: Soheil El-azzouni, Stanley Chen, Sara Halawa, Yuxin (Tiffany) Tian and Kimberly Young.
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Type 2 Diabetes. How it works
 
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Type 2 diabetes has become a pandemic and is showing no signs of slowing down. Today, the estimated worldwide prevalence of type 1 and 2 diabetes is close to 300 million. This number is predicted to rise to 439 million by 2030, with type 2 diabetes accounting for about 90% of these cases. Individuals with type 2 diabetes are often told by their doctors that their disease can be effectively managed with healthy eating, regular exercise and blood sugar monitoring. These students have created a series of three videos that simplify the complex disease process of type 2 diabetes in the hopes that better understanding will motivate patients to better manage their disease. In this video, the students use a "pizza delivery" analogy to explain what is happening when insulin, a hormone produced by the body, ceases to carry out its function. Learning objectives: - Understand the disease mechanisms underlying type 2 diabetes - Understand the link between obesity and insulin resistance - Understand the negative impacts of high blood glucose - Learn why it is so important to effectively manage Type 2 diabetes
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Knowledge Translation
 
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An introduction to knowledge translation and a brief description of the knowledge-to-action model. This video was created by Anamika Mishra in the McMaster Demystifying Medicine Program. Copyright McMaster University 2016 References: Graham, I. D., Logan, J., Harrison, M. B., Straus, S. E., Tetroe, J., Caswell, W. and Robinson, N. (2006), Lost in knowledge translation: Time for a map?. J. Contin. Educ. Health Prof., 26: 13–24. doi:10.1002/chp.47 Morris, Z. S., Wooding, S., and Grant, J. The answer is 17 years, what is the question: understanding time lags in translational research. J R Soc Med 2011; 104: 510–20 McGlynn, E., Asch, S. M., Adams, J., Keesey, J., Hicks, J., DeCristofaro, A., and Kerr, E.A. The quality of health care delivered to adults in the United States. N Engl J Med 2003; 348:-2635-2645. Claude, K. M., Juvenal, K. L., and Hawkes, M. Applying a knowledge-to-action framework for primary prevention of spina bifida in tropical Africa. Maternal & child nutrition. 2012 Apr;8(2):174–84.
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What is rabies?
 
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Animal bites always leads to the fear of contracting rabies, and newspapers readily report rabies outbreaks. Have you ever wondered what makes rabies so newsworthy? What makes rabies a serious infection? How does it affect our body? What countermeasures do we have to fight it? This video explores the answers to all of these questions. This video was made by Archita Srinath, Haider Abed, Akshay Venkatesh, Kyra Posterski, and Cindy Li. Copyright McMaster University 2016 References Dietzschold, B., Faber, M., & Schnell, M. J. (2003). New approaches to the prevention and eradication of rabies. Expert review of vaccines , 2 (3), 399406. Hemachudha, T., Laothamatas, J., & Rupprecht, C. E. (2002). Human rabies: a disease of complex neuropathogenetic mechanisms and diagnostic challenges. The Lancet Neurology, 1(2), 101109. Leung, A. K., Davies, H. D., & Hon, K. L. E. (2007). Rabies: epidemiology, pathogenesis, and prophylaxis. Advances in therapy, 24(6), 13401347. Lite, J. (2008). Medical Mystery: Only One Person Has Survived Rabies without Vaccine But How?. Scientific American, 4. Pleasure, S. J., & Fischbein, N. J. (2000). Correlation of clinical and neuroimaging findings in a case of rabies encephalitis. Archives of neurology , 57 (12), 17651769. Schnell, M. J., McGettigan, J. P., Wirblich, C., & Papaneri, A. (2010). The cell biology of rabies virus: using stealth to reach the brain. Nature Reviews Microbiology , 8 (1), 5161.
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How do Kids get Ear Infections?
 
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This video outlines a basic overview of ear infections for children. This video is meant only to educate patients about ear infections and answer questions about the infection. This video was made by seventh grade student Hiba Khan of Hillfield Strathallan College in collaboration with the McMaster Demystifying Medicine Program. Please let us know how we can improve our videos and which questions should be developed below. Copyright McMaster University 2016
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